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A Review of the Current Role of Blood Clotting Analyzers in Clinical Practice

[ Vol. 17 , Issue. 3 ]

Author(s):

Karan Sarode*, Saad S. Hussain, Alan Tyroch and Debabrata Mukherjee   Pages 167 - 179 ( 13 )

Abstract:


Background: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography, and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies, VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma, obstetric emergencies, and liver transplant.

Conclusion: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality.

Keywords:

Viscoelastic tests, clot analyzer, coagulopathy, trauma, surgery, coagulation tests.

Affiliation:

Paul L. Foster School of Medicine, El Paso, Texas, TX, Division of Cardiology, Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, Department of Surgery, Texas Tech University Health Sciences Center, El Paso, TX, Division of Cardiology, Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX

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