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Impact of the Fontan Operation on Organ Systems

[ Vol. 19 , Issue. 3 ]

Author(s):

Miriam Michel*, Manuela Zlamy, Andreas Entenmann, Karin Pichler, Sabine Scholl-Bürgi, Daniela Karall, Ralf Geiger, Christina Salvador, Christian Niederwanger and Hideo Ohuchi   Pages 205 - 214 ( 10 )

Abstract:


In patients having undergone the Fontan operation, besides the well discussed changes in the cardiac, pulmonary and gastrointestinal system, alterations of further organ systems including the hematologic, immunologic, endocrinological and metabolic are reported. As a medical adjunct to Fontan surgery, the systematic study of the central role of the liver as a metabolizing and synthesizing organ should allow for a better understanding of the pathomechanism underlying the typical problems in Fontan patients, and in this context, the profiling of endocrinological and metabolic patterns might offer a tool for the optimization of Fontan follow-up, targeted monitoring and specific adjunct treatment.

Keywords:

Endocrinology, follow-up, fontan, gastroenterology, hepatology, hematology, immunology, metabolism.

Affiliation:

Department of Pediatrics III, Division of Cardiology, Pulmology, Allergology, and Cystic Fibrosis, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics, Vienna Medical University, Währinger Gürtel 16, 1090 Vienna, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics III, Division of Cardiology, Pulmology, Allergology, and Cystic Fibrosis, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department of Pediatrics I, Innsbruck Medical University, Anichstraße 35, 6020 Innsbruck, Department for Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565

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